Objective: To assess the effects of Fenofibrate on myocardial remodeling in spontaneous hypertensive rats(SHR) by Echocardiography. Methods: Eightteen 8-week-old spontaneous hypertensive rats were randomly divided into two groups : Fenofibrate group ( n = 10) , SHR-controlled group ( n = 8) . The same week-old Wistar-kyoto(WKY) rats group ( n = 8) was also randomly selected.The Fenofibrate group were given drugs (Fenofibrate 60mg/kg.d
-1 )for 8 weeks. At the beginning,ending of the experiment,
echocardiographic scan was performed in each group. At t